Start Date
2018
Description
Indolizines are a versatile heterocyclic core found frequently in pharmaceutical targets for a wide range of therapeutic areas, including anti-tumor treatments,1 an inhibitor of Lp-PLA2, 2 and antagonists of CRTH2, 3 (Figure 1). As such, efficient synthetic methods, with broad substrate scope, for the preparation of substituted indolizines are of significant importance
Recommended Citation
Van De Burg, Jaimie E.; Boss, Benjamin L.; and Anderson, Carolyn E., "Synthesis of Trisubstituted Indolizines: Substitution, on the Pyridine Ring" (2018). Summer Research. 15.
https://digitalcommons.calvin.edu/summer_research/2018/Posters/15
Included in
Synthesis of Trisubstituted Indolizines: Substitution, on the Pyridine Ring
Indolizines are a versatile heterocyclic core found frequently in pharmaceutical targets for a wide range of therapeutic areas, including anti-tumor treatments,1 an inhibitor of Lp-PLA2, 2 and antagonists of CRTH2, 3 (Figure 1). As such, efficient synthetic methods, with broad substrate scope, for the preparation of substituted indolizines are of significant importance