Start Date
2021
Description
Radiolabeled low molecular weight peptides (LMW Peps) bind to highly expressed antigens on tumor cells (unexpressed on healthy cells) and deliver α-particle radiation to the tumor. They are cleared in urine through the kidney where the enzyme neprilysin (NEP) in the brush border membrane resides
Recommended Citation
Doorn, Eric; Li, Mengshi; Baumhover, Nicholas; and Schult, Michael K., "Reduce the Off-target Accumulation of Radiopharmaceuticals in Kidney Using Nephilysin-activated Cleavable Linkers" (2021). Summer Research. 15.
https://digitalcommons.calvin.edu/summer_research/2021/Posters/15
Included in
Reduce the Off-target Accumulation of Radiopharmaceuticals in Kidney Using Nephilysin-activated Cleavable Linkers
Radiolabeled low molecular weight peptides (LMW Peps) bind to highly expressed antigens on tumor cells (unexpressed on healthy cells) and deliver α-particle radiation to the tumor. They are cleared in urine through the kidney where the enzyme neprilysin (NEP) in the brush border membrane resides