Start Date

2023

Description

Cells have several mechanisms in place to help maintain overall cellular homeostasis and survival. One example is autophagy, a self-recycling process in the cell that serves to breakdown damaged biomolecules into smaller components that can either be used to generate new biomolecules or broken down completely for energetic purposes. Autophagy is also used during periods of stress or starvation where cells can upregulate this "self-recycling" pathway to break down cellular components as a survival mechanism. Recently, a new domain on the endoplasmic reticulum, the omegasome, has been linked to the autophagic pathway, serving as the initial source for autophagosome formation

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Jan 1st, 12:00 AM

DFCP1 WT Puncta Accumulation in U2OS Cells

Cells have several mechanisms in place to help maintain overall cellular homeostasis and survival. One example is autophagy, a self-recycling process in the cell that serves to breakdown damaged biomolecules into smaller components that can either be used to generate new biomolecules or broken down completely for energetic purposes. Autophagy is also used during periods of stress or starvation where cells can upregulate this "self-recycling" pathway to break down cellular components as a survival mechanism. Recently, a new domain on the endoplasmic reticulum, the omegasome, has been linked to the autophagic pathway, serving as the initial source for autophagosome formation