Start Date

2023

Description

Glycerides are a type of lipid, and are comprised of a hydrophilic head group and one or more hydrophobic tail groups. Monoglycerides have glycerol head group, and one fatty acid chain as a tail group (Fig 1). They form interesting and complex structures/phases at different temperatures (Fig 2). Monoglycerides have many applications in drug delivery, protein crystallization scaffolds, and nanoscale templates (Seper et al). However, even though they are so ubiquitous, the measurements we have of monoglycerides such as monoolein are sparse in the literature, and the data that exist are contradictory; there is a need for systematic density measurements. This summer's research is devoted to that effort.

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Jan 1st, 12:00 AM

Measuring Monoglyceride Densities via Pycnometry

Glycerides are a type of lipid, and are comprised of a hydrophilic head group and one or more hydrophobic tail groups. Monoglycerides have glycerol head group, and one fatty acid chain as a tail group (Fig 1). They form interesting and complex structures/phases at different temperatures (Fig 2). Monoglycerides have many applications in drug delivery, protein crystallization scaffolds, and nanoscale templates (Seper et al). However, even though they are so ubiquitous, the measurements we have of monoglycerides such as monoolein are sparse in the literature, and the data that exist are contradictory; there is a need for systematic density measurements. This summer's research is devoted to that effort.