Start Date

2023

Description

The Endoplasmic Reticulum (ER) is an organelle that aids in the production and distribution of proteins in eukaryotic cells. The ER is one continuous structure composed of bilayer membrane; it is organized into domains like long, thin tubes and flat sheets. ER morphology has implications for many cellular functions and for conditions like Alzheimer's disease. Proteins move through and are processed in the ER on their way to other parts of the cell, eventually accumulating at ER Exit Sites (ERES) before being sent to the Golgi apparatus in vesicles. Since the ER coordinates protein movement and processing for the whole cell, protein dynamics in the ER may have a large effect on cellular function.

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Jan 1st, 12:00 AM

ER Morphology and Dynamics

The Endoplasmic Reticulum (ER) is an organelle that aids in the production and distribution of proteins in eukaryotic cells. The ER is one continuous structure composed of bilayer membrane; it is organized into domains like long, thin tubes and flat sheets. ER morphology has implications for many cellular functions and for conditions like Alzheimer's disease. Proteins move through and are processed in the ER on their way to other parts of the cell, eventually accumulating at ER Exit Sites (ERES) before being sent to the Golgi apparatus in vesicles. Since the ER coordinates protein movement and processing for the whole cell, protein dynamics in the ER may have a large effect on cellular function.